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Kasturi Chakraborty

 

Current Research

    DNA nanodevices can provide functional readout on chemical cues affecting various pathways
    in cellulo and even in vivo.  My research involves studying the role of chloride in different sub- cellular compartments using a DNA scaffold based ratiometric chloride sensor.

Education

PhD. - (2013-present) - under the guidance of Prof. Yamuna Krishnan Department of Chemistry, University of Chicago.

MS, Chemistry – Organic Chemistry Specialization (2010-2012) University of Pune, Pune, Maharashtra, India

BS, Chemistry Honors (2007-2010).
St. Stephen's College, University of Delhi, New Delhi, India

Research Experience

National Chemical Laboratory (NCL), Pune, India. (2012)
6 month Research Project on synthesis of isomeric corniculatolides

National Centre for Biological Sciences (NCBS), Bangalore, India (2011)
2 month Research Project on study of a colorimetric sensor based on GNP aggregation mediated by A-motif formation.

IIT Kanpur, India (2009)
2 month Research Project on the study of encapsulation of proteins

Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India. (2008)

2 month Research Project on study and synthesis of various analogues of a peptide fragment
Aβ16-22 of Aβ protein whose aggregation is seen in Alzheimers.

Publications:

  • Chakraborty, K., Leung, K., and Krishnan, Y.* (2017) High lumenal chloride in the lysosome is critical for lysosome function. eLife, in press
  • Veetil, A.T., Chakraborty, K.,† Xiao, K.,† Minter, R. M.,† Sisodia, S. S., and Krishnan, Y.* (2017) Cell targetable DNA nanocapsules for spatiotemporal release of caged bioactive small molecules. Nature Nanotechnology, in press († both authors have contributed equally)
  • Characterization of Chemical Modification of Tryptophan by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry.
  • Sundari, C. S.; Chakraborty, K.; Nagaraj, R.; Jagannadham, M. V. Protein and Peptide Letters, Volume 17, Number 2, February
    2010 , pp. 168-171(4)  
  • Characterization of Chemical Modification of Tryptophan by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry. Sundari, C. S.; Chakraborty, K.; Nagaraj, R.; Jagannadham, M. V. Protein and Peptide Letters, Volume 17, Number 2, February
    2010 , pp. 168-171(4)  
  • Tunable, colorimetric DNA-based pH sensors mediated by A-motif formation. Saha, Sonali; Chakraborty, Kasturi; Krishnan, Yamuna. Chem. Commun., , 2012, 48, 2513-
    2515 DOI: 10.1039/C2CC16347K, Communication  
  • Synthesis of isomeric corniculatolides. Gajanan N. Raut, Kasturi Chakraborty, Priyanka
    Verma,  Rajesh  S.  Gokhale, D. Srinivasa Reddy .  Tetrahedron  Letters  53  (2012)
    6343– 6346  
  • Research Scholar, Department of Chemistry, University of
    Chicago, GCIS, E305A, 929,
    East 57th St, Chicago, IL
    60637.

    Email:kasturi[at]uchicago.edu

    kasturichakraborty[at]gmail.com


     

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